Aurora

3D Spatial Biology Solution

Combining cutting-edge 3D tissue imaging instruments, powerful data processing software, and comprehensive image analysis services.

TM

Tissue Imaging: 3Di 

Hybrid Open Top Light Sheet (HOTLS) Microscope

Our 3Di Hybrid Open Top Light Sheet (HOTLS) Fluorescent Microscope transforms whole 3D tissue samples into detailed digital models, capturing unparalleled biological detail far beyond standard 2D histology. Its innovative design enables multi-resolution imaging with the flexibility to adapt to diverse research needs, thanks to an expansive 1 cm working distance and scan dimensions of 12.5cm x 7cm.

The “Scout” imaging pathway delivers fast, whole-tissue views to streamline workflows, while the “Zoom” pathway achieves exceptional high-resolution clarity.

With its open-top format, the 3Di HOTLS supports high-throughput imaging, processing dozens to hundreds of samples in one session, simplifying lab workflows, and enabling groundbreaking research across diverse applications. Learn more in the Nature Methods paper introducing this system.

Data Management: 3Dm

Automated registration, alignment, and flat field correction for large data sets

Our 3Dm data management solution is engineered for the automated processing of large and ultra-large data sets. It includes features for flat-field correction, precise tile stitching, and seamless registration of multiple fluorescent channels. This comprehensive tool automatically aligns images post-imaging, surpassing the speed and efficiency of open-source options and validated for data sizes exceeding 4 terabytes.

Image Analysis: 3Dai

Data analytics and quantitative insights services

Our 3Dai image analysis tools provide sophisticated data analytics and quantitative insights to help you extract and interpret complex biological data. This platform supports both research and drug development, enhancing your workflow with powerful analytics that bring unparalleled precision and speed to 3D biological image processing. Leverage this advanced technology to propel your scientific initiatives forward with accuracy and efficiency.

Dive into a compelling example of the complete Aurora Workflow, featuring an advanced 3D imaging study of heart architecture.

This video highlights groundbreaking insights into murine cardiac vasculature, offering detailed analyses such as cell counts, vessel dimensions, distance measurements, and branching patterns.

Our workflows are tailored to meet your specific research needs, Contact us to discover how we can elevate your tissue analysis and help you lead the 3D imaging revolution.