3D fat pad.jpg

3D spatial biology platform

Turn intact tissue into quantitative 3D data

Aurora 3D™ connects intact tissue imaging, spatial profiling, and AI-powered analysis to generate quantitative biological readouts.

Trusted by leading research teams and eight of the top 10 pharmaceutical companies

Intact tissue imaging

High-resolution 3D data

AI-powered quantitative analysis

End-to-end spatial biology

Aurora 3D™ Spatial Biology Solution

From intact tissue to quantitative 3D insight

An end-to-end platform for high-resolution whole-tissue imaging, automated volumetric data processing, and AI-powered quantitative analysis.

01

The platform

One connected workflow from imaging to analysis

Alpenglow Biosciences 3Di Hybrid Open-Top Light-Sheet microscope

3Di

Image intact tissue

Dual-path open-top light-sheet imaging for whole samples and high-resolution regions of interest.

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Alpenglow Biosciences 3Dm volumetric data management interface

3Dm

Process volumetric data

Align, organize, and prepare large multichannel volumetric datasets for analysis and review.

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Alpenglow Biosciences 3Dai AI-powered analysis interface

3Dai

Generate quantitative readouts

Quantify cells, structures, and spatial patterns across the complete tissue volume.

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Explore the Aurora 3D™ platform
02 Why 3D?

See what thin sections can miss

Conventional slides capture selected tissue planes. Intact 3D imaging preserves spatial context across the full tissue volume, helping reveal structures, cell neighborhoods, vessels, nerves, and patterns that may be missed in 2D.

Why 3D tissue imaging matters See 3D tissue examples
High-resolution 3D imaging of an entire mouse brain
03

Applications

3D tissue imaging applications across tissues

3D tissue imaging example for dermatology

Dermatology

Map immune cells, nerves, follicles, and tissue architecture across intact skin.

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3D tissue imaging example for immuno-oncology

Immuno-Oncology

Visualize tumor architecture, immune organization, and spatial patterns in 3D.

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whole rat heart iamging in 3D

Multi-Field Capabilities

Apply 3D tissue imaging across organs, model systems, and translational workflows.

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Multimodal tissue intelligence

Summit AI

Turn full-sample tissue data into earlier, higher-confidence development decisions

Summit AI™ analyzes full-sample 3D imaging and connects multimodal data to generate quantitative tissue signatures and spatial profiles. These insights help teams identify treatment effects earlier, reduce development risk, and make stronger clinical and competitive decisions.

Ways to work with Alpenglow

Access the workflow your way

3Di HOTLS

Image in-house

Bring scalable intact-tissue imaging to your facility.

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Summit AI™

Analyze your data

Generate quantitative tissue signatures from full-sample data.

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Solutions for your role

Start with the priorities of your team

Explore role-specific solutions for integrating 3D tissue imaging and quantitative analysis into your work.

View all role solutions

About Alpenglow

Building the tools and partnerships advancing 3D spatial biology

Alpenglow Biosciences develops integrated 3D tissue imaging and AI-powered analysis solutions for research, drug development, and diagnostic innovation.

Latest from Alpenglow

Where to meet us and company updates

Upcoming scientific events, partnerships, platform developments, and announcements from Alpenglow Biosciences.

Your next step

Bring your tissue question into 3D

Share your sample type, markers, and study goals. Alpenglow can help determine whether imaging services, an in-house Aurora 3D™ workflow, or quantitative analysis is the right path for your team.

Intact tissue imaging

3D imaging of intact heart tissue showing vascular structures

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