See a hair follicle in stunning 3D detail, from the bulb to the dermal papilla. Using PGP9.5 and TO-PRO-3 staining, this advanced imaging highlights sensory nerve fibers and nuclei, transforming hair research and alopecia areata detection.

3D imaging transforms dermatological research by revealing intricate scalp tissue structures with TO-PRO-3, CD45, and PGP9.5 staining. See the difference between full 3D visualization and traditional 2D slices, unlocking new insights into atopic dermatitis, alopecia areata, and more.

Experience the power of 3D imaging in dermatology with this high-resolution video of an atopic dermatitis skin biopsy. Visualizing nerves (PGP9.5), immune cells (CD45), and nuclear structures (TOPRO3) in true spatial context, this technology reveals details impossible to capture with traditional tissue sections—offering unprecedented clarity and quantifiable insights for research.

2 mm pig muscle section stained with CD31 (green) for endothelial cells and YO-PRO-1 (red) for nuclei, revealing the intricate vascular network in extraordinary detail.

Using our Hybrid-Open-Top Light Sheet microscope, the 3Di, we seamlessly transition from fast, low-resolution overviews to high-resolution imaging of key regions. This unique approach delivers unparalleled speed and precision, uncovering insights impossible with 2D methods.

Journey through the delicate nerve structures of the epidermis and dermis at low resolution, and zoom in for an awe-inspiring close-up of lymphocyte distribution around these dynamic networks. This visualization not only captures the stunning complexity of skin biology but also delivers actionable insights, propelling advancements in dermatology research.

CD45 staining in whole skin biopsy captured through advanced 3D imaging.

Explore the dynamic interplay of lymphocyte distribution around the nerve network and the complex cellular architecture of the skin.

Appreciate the result of precise data management and image segmentation that unveils lymphocyte distribution around nerves with remarkable accuracy.

Delve into the intricate details of a lesional atopic dermatitis sample captured with cutting-edge 40X high-resolution 3D imaging. The sample is vividly stained with TO-PRO-3 blue for nuclei, PGP 9.5 white for nerves, and CD45 yellow for lymphocytes. Marvel at the precise preservation of epidermal and dermal structures and the clear visualization of immune-cell clusters in close proximity to specific nerve fibers.

Explore this cutting-edge 3D imaging of Human Normal Adjacent Colorectal Cancer

Experience the intricate architecture of human placenta tissue in this captivating 3D video, designed to showcase the power of advanced spatial biology.

This video captures 3D imaging of a whole murine heart, highlighting the complexity and detail of vascular structures. Smooth muscle actin (SMA) stains the blood vessels in green, providing a vivid view of their architecture, while mural cells are highlighted in purple.

Low resolution image of human tonsil measuring up to 3mm in x,y,z, stained with Biocare Bu32 anti-CD21. This antibody has been optimized for a variety of human tissue including FFPE samples.

High resolution image of human tonsil measuring up to 3mm in x,y,z, stained with Biolegend anti-CD45RO. This antibody has been optimized for a variety of human tissue including FFPE samples.

This video presents low-resolution (scout) imaging of a human dorsal root ganglion (DRG) sample provided by AnaBios. The sample features computational H&E staining, with ToPro-3 highlighting nuclei and Eosin-capturing protein structures.

This video presents high-resolution (zoom) imaging of a human dorsal root ganglion (DRG) sample provided by AnaBios. The sample features computational H&E staining, with ToPro-3 highlighting nuclei and Eosin-capturing protein structures. A fascinating visualization offering insights into DRG tissue composition.