Whole murine heart staining and imaging

This video captures 3D imaging of a whole murine heart, highlighting the complexity and detail of vascular structures. Smooth muscle actin (SMA) stains the blood vessels in green, providing a vivid view of their architecture, while mural cells are highlighted in purple.

Starting with large vessels, the video gradually zooms into specific regions, showcasing the structural intricacies at progressively higher resolutions. This transition from broad tissue structures to single-cell resolution reveals the clear, detailed presence of pericytes surrounding the vessels.

Explore the inside of one blood vessel with Alpenglow's logo and witness pericytes wrapping around the vessel. This is the first step in transforming stunning visuals into meaningful data. With our end-to-end platform, we can quantify vessel branching, cells, distances, and more.

Leveraging Alpenglow’s advanced imaging settings with the Aurora 3Di, it is possible to seamlessly shift from large-scale, low-resolution imaging (Scout) to focused, high-resolution single-cell views (Zoom). This flexibility—scaling from tiny organoids to entire organs—creates vast analytical potential, empowering researchers to explore complex biological questions with newfound clarity and precision.