Skin biopsy in 3D: from low to high resolution

Written By Elisa Barbieri

Immerse yourself in another breathtaking 3D skin punch biopsy, vividly stained to unveil:

PGP 9.5 (white) – tracing the intricate nerve networks
TO-PRO-3 (blue) – marking the nuclei
CD45 (yellow) – highlighting lymphocytes

Journey through the delicate nerve structures of the epidermis and dermis at low resolution, and zoom in for an awe-inspiring close-up of lymphocyte distribution around these dynamic networks. This visualization not only captures the stunning complexity of skin biology but also delivers actionable insights, propelling advancements in dermatology research.

Elisa Barbieri
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2 mm pig muscle section stained with CD31 and YO-PRO-1
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CD45 staining in whole skin biopsy