Imaging Facility
Alpenglow Biosciences’ 3Di Hybrid Open Top Light Sheet Microscope (3Di HOTLS) is the ideal tool for any imaging facility seeking versatile, high-quality imaging across a broad spectrum of biological samples.
From organoids to animal model biopsies and human tissues, the 3Di HOTLS allows researchers to observe intricate 3D structures in their natural, unaltered state, eliminating the need to slice or alter the sample.
Key advancements in this cutting-edge platform empower researchers with capabilities such as simplified whole-tissue imaging through the “Scout” imaging pathway. This feature enables full-tissue views in a fraction of the time, streamlining workflows and allowing scientists to quickly pinpoint areas of interest for further analysis. The “Zoom” pathway provides high-resolution clarity for studies requiring exceptional detail, delivering precise insights into cellular distributions and complex fibrotic or vascular structures.
With a 1 cm working distance and scan dimensions of 12.5 cm x 7 cm, the microscope is adaptable to a variety of experiments, from small-scale studies to extensive tissue investigations. Whether working with complex organoid cultures or entire tissue slices, researchers can rely on consistent, high-resolution imaging with minimal sample preparation.
The open-top design ensures intuitive and flexible sample handling, reducing setup time and simplifying lab workflows. This user-friendly feature enhances accessibility, helping labs focus more on imaging and less on preparation.
These advancements make the 3Di HOTLS an invaluable addition to any imaging facility seeking both flexibility and precision to tackle challenges in fields ranging from immuno-oncology to organoid development.