Revolutionizing how we use pathology

ABOUT US

Alpenglow’s story began when CEO Nicholas (Nick) Reder MD MPH, then a medical resident in the pathology department at the University of Washington, reached out to Dr. Jonathan Liu of the mechanical engineering department with a technical challenge.  While performing the conventional task of slicing tumor samples, preparing for analysis, then observing under a microscope, Nick thought there had to be a better way.  He asked Dr. Liu if there was a technology that could rapidly scan tissue samples to examine and analyze these tumors in a more efficient and automated manner.  This basic challenge led to a collaboration between Nick, Dr. Liu, Dr. Adam Glaser, and Dr. Larry True that resulted in the development of a patented open-top light-sheet microscope technology. The team spun out Lightspeed Microscopy to commercialize this promising technology with the potential to accelerate drug development and improve clinical diagnostics.  Since then, the platform has been AI-enabled with cloud-based computing and analysis to produce remarkable 3D spatial analysis of tissue samples at high speed.   

In 2022, the company rebranded as Alpenglow Biosciences to reflect this evolution as well as an expanded research partnership offering. The naming was inspired by the alpenglow effect, an optical phenomenon that appears as brilliant colors on alpine landscapes as the sun shines its first and last light each day. The name is an analogy to how Alpenglow Biosciences sheds new light on the field of drug development and clinical diagnostics, revealing unique insights that can only be delivered with its AI-enabled 3D imaging platform.

Our Investors



University of Washington scientific co-founders begin working on high throughput 3D microscopy
— 2014
Lightspeed Microscopy, Inc. founded
— 2018
Launched commercial operations, initially partnering with 4 pharmaceutical companies
— 2020
Raised $4M in venture financing to scale our solution for the pharma R&D market
— 2021
Rebranded as Alpenglow Biosciences

Unveiled the Aurora platform, consisting of integrated imaging, data processing and analysis
— 2022
Hosted the world’s first 3D spatial summit
Launched the first clinical trial using 3D spatial biology
— 2023
Launched our end-to-end assays, the 3D Derm Score and 3D I/O Pro delivering tissue to insights solutions
— 2024