Whole sample imaging of a Lesional Atopic Dermatitis punch biopsy highlighting innervation within the Dermis and Epidermis at low power resolution

Lesional Atopic Dermatitis sample stained with TO-PRO-3 (blue—nuclear stain), PGP9.5 (white—nerves0, and CD3 (green—cells). Image reproduced with permission from Incyte Corporation. Low resolution imaging of entire punch biopsy highlighting the innervation of the Epidermis, Dermis and immune infiltration

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Identifying cytotoxic T-cells in cleared, thick, tissue samples

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Lesional Atopic Dermatitis sample highlighting fine innervation of the Epidermal layer (40X magnification)