Turn Tissue into Data with 3D Tissue Imaging and Spatial AI

Intact 3D tissue imaging, spatial profiling, and quantitative AI analysis in a single, end-to-end imaging platform.

See What You’ve Been Missing: Ground-Truth 3D Data

Alpenglow captures whole tissues intact in 3D, revealing architecture and cellular context with decision-grade clarity that conventional slides cannot provide.

Aurora™ platform, from tissue to usable data

  • Image intact tissue

  • Process and manage large volumes

  • Quantify with AI for reproducible segmentations and metrics

Why ground-truth 3D matters

Whole-tissue imaging preserves architecture and scale
• Preserve true 3D tissue structure across volumes
• Measure cell populations and distances
• Align imaging with outcomes for model training

Tailored Solutions by Role
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Aurora™: 3D Spatial Biology Platform

End-to-end by design, Aurora 3D™ unifies 3D imaging, data management, and AI analysis. Select the full platform for final outputs, or use each module on its own, delivered as a service or as a system.

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3Di

Advanced Tissue Imaging

Dual-path light-sheet imaging for fast whole-sample scans and high-resolution detail capture, all managed through the user-friendly LUMI interface.

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3Dm

Automated Data Management

Automate dataset management with 3Dm™, ensuring precise alignment and handling of large data sets.

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3Dai

AI-Driven Image Analysis

Use AI-driven 3D data analysis to gain valuable insights through spatial relationship mapping, pattern detection, and distance measurements.

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Uncover Deeper Insights Through Advanced 3D Tissue Imaging

3D Image Zoom Skin Biopsy Atopic Dermatitis CD45 PGP9.5 TO-PRO-3 Alpenglow Biosciences

Dermatology

The 3D Derm Score Assay allows you to examine skin tissues with unprecedented clarity. It quantifies key structures, like nerves and immune cells, to deliver a complete view of the epidermis and dermis.

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3D imaging of Human Normal Adjacent Colorectal Cancer FFPE stained with CD8

Immuno-Oncology

​The 3D I/O Pro Assay offers a comprehensive analysis of the tumor microenvironment. This tool quantifies immune cell infiltration and stromal architecture to help you better understand cancer-immune interactions.

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3D imaging of human placenta stained with SMA in purple, HLA-G in yellow, and CD31 in cyan.

Multi-Field Capabilities

Leverage our versatile 3D imaging platform to decode complex tissue structures. It maps cellular networks and interactions across research areas, empowering breakthrough discoveries.

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Alpenglow Biosciences in the News

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ABOUT ALPENGLOW

Alpenglow Biosciences accelerates drug development and improves clinical diagnostics through AI-enabled 3D imaging technology. Our platform delivers new biological insights and more accurate data by digitizing entire samples while preserving tissue for molecular analysis. Partners benefit from exclusive technology and a greater understanding of their biology. Five of the top 10 pharmaceutical companies collaborate with Alpenglow to uncover new insights, streamline timelines, and improve success rates.

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